RESUMO
The aim of this work was to study the prevalence of biliary diseases and digestive symptoms in normal adult women. Four hundred nineteen women were chosen; of these 145 were discarded due to previous gastrointestinal diseases (20), previous gastrointestinal complaints (38) and previous cholecystectomy (85). Two hundred seventy six women were subjected to abdominal ultrasound examination; of these 53 had cholelithiasis and in three a gallbladder cancer was suspected (and confirmed by surgery). Considering women with previous cholecystectomy, cholelithiasis and gallbladder cancer, a 33.6% prevalence of biliary diseases can be inferred. An interrogation about gastrointestinal symptoms was performed to women subjected to ultrasound examinations, by 2 professionals unaware of ultrasound results. A high frequency of pyrosis, food intolerance and constipation was found, not observing differences between women with or without cholelithiasis. However, these last women had a higher frequency of upper abdominal pain. Both groups had also a high rate of previous surgical procedures.
Assuntos
Colelitíase/epidemiologia , Gastroenteropatias/epidemiologia , Adulto , Fatores Etários , Idoso , Doenças Biliares/epidemiologia , Doenças Biliares/etiologia , Distribuição de Qui-Quadrado , Chile/epidemiologia , Colelitíase/complicações , Estudos Transversais , Feminino , Gastroenteropatias/etiologia , Azia/epidemiologia , Azia/etiologia , Humanos , Pessoa de Meia-Idade , Prevalência , Estudos ProspectivosRESUMO
We report four episodes of mushroom poisoning that occurred between 1986 and 1990 in the province of Malleco. Twenty five of 36 individuals who ingested the mushroom became ill; they had an acute gastroenteritis that was followed in 7 by an acute hepatitis and in one by a massive upper gastrointestinal bleeding. Three subjects with fulminant hepatic failure and the subject with the massive bleeding died. Amanita gemmate (strain described as toxic in Chile since 1967) was found in two episodes and Amanita sp in one. The clinical picture is similar to that described for Amanita phaloides. The treatment is symptomatic but penicillin and silymarin may have an antitoxic action. The importance of warning the population about the existence of toxic mushrooms in Chile is emphasized.
Assuntos
Intoxicação Alimentar por Cogumelos , Adulto , Amanita , Doença Hepática Induzida por Substâncias e Drogas/etiologia , Doença Hepática Induzida por Substâncias e Drogas/terapia , Pré-Escolar , Chile , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Intoxicação Alimentar por Cogumelos/complicações , Intoxicação Alimentar por Cogumelos/terapiaRESUMO
We report 4 episodes of mushroom poisoning that ocurred before 1986 and 1990 in the province of Malleco. 25 of 36 individuals who ingested the mushroom became ill; they had an acute gastroenteritis that was followed in 7 by an acute hepatitis and in 1 by a massive upper gastrointestinal bleeding. Three subjects with fulminant hepatic failure and the subject with the massive bleeding died. Amanita gemmata (strain described as toxic in Chile since 1967) was found in 2 episodes and Amanita sp in 1. The clinical picture is similar to that described for Amanita phaloides. The treatment is symptomatic but penicillin and silymarin may have an antitoxic action. The importance of warning the population about the existence of toxic mushrooms in Chile is emphasized
Assuntos
Humanos , Masculino , Feminino , Pré-Escolar , Adulto , Pessoa de Meia-Idade , Amanita/patogenicidade , Micotoxicose/epidemiologia , Amanitinas/toxicidade , Hepatite/etiologia , Micotoxicose/terapiaRESUMO
Se cita por primera vez en Chile Amanita phalloides (Vaill. ex Fr) Secr., junto a su descripción macro y microscópica, y algunos aspectos de su ecología. Se aporta información sobre sus toxinas, métodos de detección y cuadro clínico de la intoxicación faloidiana
Assuntos
Humanos , Amanita/isolamento & purificação , Micotoxicose/diagnóstico , Amanita/classificação , Amanita/ultraestrutura , Amanita/virologia , Árvores/parasitologia , Basidiomycota/patogenicidade , Micotoxicose/complicações , Micotoxicose/terapiaRESUMO
Fine structural changes of capillaries in spontaneously hypertensive rats (SHRs) under the influence of 1% NaCl were studied. In SHRs (control), 30 weeks and older, capillaries showed deformed lumina, hypertrophy of endothelial cells and matrical alterations of mitochondria. Deformed capillary lumina, fibrosis in upper stream vessels and swelling of astrocytic processes were observed in the saline-treated SHRs. The significance of these findings is discussed.